The significance of Exo1 K589E polymorphism on cancer susceptibility: evidence based on a meta-analysis.

The exonuclease1 (Exo1) gene is a key component of mismatch repair (MMR) by resecting the damaged strand, which is the only exonuclease involved in the human MMR system. The gene product is a member of the RAD2 nuclease family and functions in DNA replication, repair and recombination. However, whet...

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Bibliographic Details
Main Authors: Fujiao Duan, Chunhua Song, Liping Dai, Shuli Cui, Xiaoqin Zhang, Xia Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24810280/?tool=EBI