The fading of reported effectiveness. A meta-analysis of randomised controlled trials

<p>Abstract</p> <p>Background</p> <p>The "real" effect size of a medical therapy is constant over time. In contrast, the effect size reported in randomised controlled trials (RCTs) may change over time because the sum of all kinds of bias influencing the repor...

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Bibliographic Details
Main Authors: Weiss Christel, Gehr Bernhard T, Porzsolt Franz
Format: Article
Language:English
Published: BMC 2006-05-01
Series:BMC Medical Research Methodology
Online Access:http://www.biomedcentral.com/1471-2288/6/25