Knockout of the HaREase Gene Improves the Stability of dsRNA and Increases the Sensitivity of Helicoverpa armigera to Bacillus thuringiensis Toxin

Knockout of the HaREase Gene Improves the Stability of dsRNA and Increases the Sensitivity of Helicoverpa armigera to Bacillus thuringiensis Toxin

Double-stranded RNA (dsRNA)-induced genes are usually related to RNA interference (RNAi) mechanisms and are involved in immune-related pathways. In a previous study, we found a lepidopteran-specific nuclease gene REase that was up-regulated by dsRNA and that affected RNAi efficiency in Asian corn bo...

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Bibliographic Details
Main Authors: Ruobing Guan, Qiuyan Chen, Haichao Li, Shaoru Hu, Xuexia Miao, Guirong Wang, Bin Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Physiology
Subjects:
HaREase
CRISPR/Cas9 system
RNAi efficiency
Bt resistance
dsRNA stability
insect immune
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01368/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.01368/full

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