Endothelin-1 Inhibits Apoptosis in Prostate Cancer

Endothelin-1 Inhibits Apoptosis in Prostate Cancer

Endothelin-1 (ET-1), produced by the prostate epithelia, likely plays an important role in the progression of prostate cancer. ET-1 can bind two receptor subtypes; generally, binding of the endothelin receptor A (ETA) induces a survival pathway, whereas binding of the endothelin receptor B (ETB) me...

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Bibliographic Details
Main Authors: Joel B. Nelson, Michael S. Udan, Georgi Guruli, Beth R. Pflug
Format: Article
Language:English
Published: Elsevier 2005-07-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Endothelin-1
apoptosis
prostate cancer
endothelin receptors
Akt
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558605800843

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http://www.sciencedirect.com/science/article/pii/S1476558605800843

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