Involvement of the arachidonic acid cytochrome P450 epoxygenase pathway in the proliferation and invasion of human multiple myeloma cells

Involvement of the arachidonic acid cytochrome P450 epoxygenase pathway in the proliferation and invasion of human multiple myeloma cells

Cytochrome P450 (CYP) epoxygenases and the metabolites epoxyeicosatrienoic acids (EETs) exert multiple biological effects in various malignancies. We have previously found EETs to be secreted by multiple myeloma (MM) cells and to be involved in MM angiogenesis, but the role of the arachidonic acid c...

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Bibliographic Details
Main Authors: Jing Shao, Hongxiang Wang, Guolin Yuan, Zhichao Chen, Qiubai Li
Format: Article
Language:English
Published: PeerJ Inc. 2016-04-01
Series:PeerJ
Subjects:
Multiple myeloma
Proliferation
Epoxyeicosatrienoic acids
Cytochrome p450
Apoptosis
Migration
Online Access:https://peerj.com/articles/1925.pdf

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https://peerj.com/articles/1925.pdf

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