Evaluation of the Antinociceptive, Antiallodynic, Antihyperalgesic and Anti-Inflammatory Effect of Polyalthic Acid

Evaluation of the Antinociceptive, Antiallodynic, Antihyperalgesic and Anti-Inflammatory Effect of Polyalthic Acid

Nonsteroidal anti-inflammatory drugs (NSAIDs) are very commonly used, but their adverse effects warrant investigating new therapeutic alternatives. Polyalthic acid, a labdane-type diterpenoid, is known to produce gastroprotection, tracheal smooth muscle relaxation, and antitumoral, antiparasitic and...

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Bibliographic Details
Main Authors: Juan Rodríguez-Silverio, María Elena Sánchez-Mendoza, Héctor Isaac Rocha-González, Juan Gerardo Reyes-García, Francisco Javier Flores-Murrieta, Yaraset López-Lorenzo, Geovanna Nallely Quiñonez-Bastidas, Jesús Arrieta
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
polyalthic acid
naproxen
isobologram
antinociception
antiallodynic effect
synergism
Online Access:https://www.mdpi.com/1420-3049/26/10/2921

Internet

https://www.mdpi.com/1420-3049/26/10/2921

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