Identification of ABC Transporter Interaction of a Novel Cyanoquinoline Radiotracer and Implications for Tumour Imaging by Positron Emission Tomography.

Identification of ABC Transporter Interaction of a Novel Cyanoquinoline Radiotracer and Implications for Tumour Imaging by Positron Emission Tomography.

<h4>Background</h4>The epidermal growth factor receptor (EGFR) is overexpressed in many cancers including lung, ovarian, breast, head and neck and brain. Mutation of this receptor has been shown to play a crucial role in the response of non-small cell lung carcinoma (NSCLC) to EGFR-targe...

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Bibliographic Details
Main Authors: Rozanna L Slade, Federica Pisaneschi, Quang-De Nguyen, Graham Smith, Laurence Carroll, Alice Beckley, Maciej A Kaliszczak, Eric O Aboagye
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0161427

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https://doi.org/10.1371/journal.pone.0161427

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