Saikosaponin-D Enhances Radiosensitivity of Hepatoma Cells under Hypoxic Conditions by Inhibiting Hypoxia-Inducible Factor-1α

Saikosaponin-D Enhances Radiosensitivity of Hepatoma Cells under Hypoxic Conditions by Inhibiting Hypoxia-Inducible Factor-1α

Background: Our previous study revealed that the combination of Saikosaponin-d (SSd) and radiation is more effective in the treatment of liver cancer than the application of either of these monotherapeutic methods. However, the molecular mechanisms of the radiosensitizing effect of SSd on liver canc...

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Bibliographic Details
Main Authors: Bao-Feng Wang, Xi-jing Wang, Hua-Feng Kang, Ming-Hua Bai, Hai-Tao Guan, Zhong-Wei Wang, Ying Zan, Ling-Qin Song, Wei-Li Min, Shuai Lin, Yan-An Cheng
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-01-01
Series:Cellular Physiology and Biochemistry
Subjects:
Hypoxia
HCC
Radiation
Cobalt chloride
HIF-1α
Online Access:http://www.karger.com/Article/FullText/356648

Internet

http://www.karger.com/Article/FullText/356648

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