Analyzing the effect of APOE on Alzheimer’s disease progression using an event-based model for stratified populations

Analyzing the effect of APOE on Alzheimer’s disease progression using an event-based model for stratified populations

Alzheimer’s disease (AD) is the most common form of dementia and is phenotypically heterogeneous. APOE is a triallelic gene which correlates with phenotypic heterogeneity in AD. In this work, we determined the effect of APOE alleles on the disease progression timeline of AD using a discriminative ev...

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Bibliographic Details
Main Authors: Vikram Venkatraghavan, Stefan Klein, Lana Fani, Leontine S. Ham, Henri Vrooman, M. Kamran Ikram, Wiro J. Niessen, Esther E. Bron
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:NeuroImage
Subjects:
Disease Progression Modeling
Event-Based Model
Alzheimer’s Disease
APOE
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811920311319

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http://www.sciencedirect.com/science/article/pii/S1053811920311319

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