Premature osteoblast clustering by enamel matrix proteins induces osteoblast differentiation through up-regulation of connexin 43 and N-cadherin.

Premature osteoblast clustering by enamel matrix proteins induces osteoblast differentiation through up-regulation of connexin 43 and N-cadherin.

In recent years, enamel matrix derivative (EMD) has garnered much interest in the dental field for its apparent bioactivity that stimulates regeneration of periodontal tissues including periodontal ligament, cementum and alveolar bone. Despite its widespread use, the underlying cellular mechanisms r...

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Bibliographic Details
Main Authors: Richard J Miron, Erik Hedbom, Sabrina Ruggiero, Dieter D Bosshardt, Yufeng Zhang, Corinna Mauth, Anja C Gemperli, Tateyuki Iizuka, Daniel Buser, Anton Sculean
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3156132?pdf=render

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http://europepmc.org/articles/PMC3156132?pdf=render

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