Truncating and missense <it>BMPR2 </it>mutations differentially affect the severity of heritable pulmonary arterial hypertension
<p>Abstract</p> <p>Background</p> <p>Autosomal dominant inheritance of germline mutations in the bone morphogenetic protein receptor type 2 (<it>BMPR2</it>) gene are a major risk factor for pulmonary arterial hypertension (PAH). While previous studies demons...
Main Authors: | , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2009-09-01
|
Series: | Respiratory Research |
Online Access: | http://respiratory-research.com/content/10/1/87 |