Truncating and missense <it>BMPR2 </it>mutations differentially affect the severity of heritable pulmonary arterial hypertension

Truncating and missense <it>BMPR2 </it>mutations differentially affect the severity of heritable pulmonary arterial hypertension

<p>Abstract</p> <p>Background</p> <p>Autosomal dominant inheritance of germline mutations in the bone morphogenetic protein receptor type 2 (<it>BMPR2</it>) gene are a major risk factor for pulmonary arterial hypertension (PAH). While previous studies demons...

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Bibliographic Details
Main Authors: Wheeler Lisa A, Phillips Charles A, Stanton Krista C, Yu Chang, Hamid Rizwan, Cogan Joy D, Phillips John A, Austin Eric D, Robbins Ivan M, Newman John H, Loyd James E
Format: Article
Language:English
Published: BMC 2009-09-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/10/1/87

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http://respiratory-research.com/content/10/1/87

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