Esculetin Ameliorates Psoriasis-Like Skin Disease in Mice by Inducing CD4+Foxp3+ Regulatory T Cells

Esculetin Ameliorates Psoriasis-Like Skin Disease in Mice by Inducing CD4+Foxp3+ Regulatory T Cells

Psoriasis is an autoimmune and inflammatory skin disease affecting around 2–3% of the world's population. Patients with psoriasis need extensive treatments with global immunosuppressive agents that may cause severe side effects. Esculetin, a type of coumarins, is an active ingredient extracted...

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Bibliographic Details
Main Authors: Yuchao Chen, Qunfang Zhang, Huazhen Liu, Chuanjian Lu, Chun-Ling Liang, Feifei Qiu, Ling Han, Zhenhua Dai
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Immunology
Subjects:
esculetin
immunosuppression
immunoregulation
psoriasis
regulatory T cell
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02092/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02092/full

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