Leptin Receptor Mediates Bmal1 Regulation of Estrogen Synthesis in Granulosa Cells

Chronobiology affects female fertility in mammals. Lepr is required for leptin regulation of female reproduction. The presence of E-box elements in the <i>Lepr</i> promoter that are recognized and bound by clock genes to initiate gene transcription suggested that circadian systems might...

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Bibliographic Details
Main Authors: Guiyan Chu, Guangjun Ma, Jingchun Sun, Youbo Zhu, Aoqi Xiang, Gongshe Yang, Shiduo Sun
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Animals
Subjects:
Online Access:https://www.mdpi.com/2076-2615/9/11/899