Use of Imaging Techniques to Illuminate Dynamics of Hematopoietic Stem Cells and Their Niches

Continuous generation of blood cells over an organism's lifetime is supported by hematopoietic stem/progenitor cells (HSPCs) capable of producing all hematopoietic cell subtypes. Adult mammalian HSPCs are localized to bone marrow and regulated by their neighboring microenvironment, or “niche.”...

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Bibliographic Details
Main Authors: Takayuki Morikawa, Keiyo Takubo
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fcell.2017.00062/full