Role of Human‐Induced Pluripotent Stem Cell‐Derived Spinal Cord Astrocytes in the Functional Maturation of Motor Neurons in a Multielectrode Array System

Role of Human‐Induced Pluripotent Stem Cell‐Derived Spinal Cord Astrocytes in the Functional Maturation of Motor Neurons in a Multielectrode Array System

Abstract The ability to generate human‐induced pluripotent stem cell (hiPSC)‐derived neural cells displaying region‐specific phenotypes is of particular interest for modeling central nervous system biology in vitro. We describe a unique method by which spinal cord hiPSC‐derived astrocytes (hiPSC‐A)...

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Bibliographic Details
Main Authors: Arens Taga, Raha Dastgheyb, Christa Habela, Jessica Joseph, Jean‐Philippe Richard, Sarah K. Gross, Giuseppe Lauria, Gabsang Lee, Norman Haughey, Nicholas J. Maragakis
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Stem Cells Translational Medicine
Subjects:
Electrophysiology
Spinal cord
Glutamate receptor
Gap junction
Glia
Online Access:https://doi.org/10.1002/sctm.19-0147

Internet

https://doi.org/10.1002/sctm.19-0147

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