Gut Bacterial Species Distinctively Impact Host Purine Metabolites during Aging in Drosophila

Gut Bacterial Species Distinctively Impact Host Purine Metabolites during Aging in Drosophila

Summary: Gut microbiota impacts the host metabolome and affects its health span. How bacterial species in the gut influence age-dependent metabolic alteration has not been elucidated. Here we show in Drosophila melanogaster that allantoin, an end product of purine metabolism, is increased during agi...

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Bibliographic Details
Main Authors: Toshitaka Yamauchi, Ayano Oi, Hina Kosakamoto, Yoriko Akuzawa-Tokita, Takumi Murakami, Hiroshi Mori, Masayuki Miura, Fumiaki Obata
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:iScience
Subjects:
Biological Sciences
Molecular Biology
Immunology
Microbiome
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220306696

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http://www.sciencedirect.com/science/article/pii/S2589004220306696

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