Circulating tumor cells in precision oncology: clinical applications in liquid biopsy and 3D organoid model
Abstract Circulating tumor cells (CTCs) are a rare subset of cells found in the blood of patients with solid tumors, which function as a seed for metastases. Cancer cells metastasize through the bloodstream either as single migratory CTCs or as multicellular groupings—CTC clusters. The CTCs preserve...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-12-01
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Series: | Cancer Cell International |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12935-019-1067-8 |