Circulating tumor cells in precision oncology: clinical applications in liquid biopsy and 3D organoid model

Abstract Circulating tumor cells (CTCs) are a rare subset of cells found in the blood of patients with solid tumors, which function as a seed for metastases. Cancer cells metastasize through the bloodstream either as single migratory CTCs or as multicellular groupings—CTC clusters. The CTCs preserve...

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Bibliographic Details
Main Authors: Chang Yang, Bai-Rong Xia, Wei-Lin Jin, Ge Lou
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-019-1067-8