How to Determine the Accuracy of an Alternative Diagnostic Test when It Is Actually Better than the Reference Tests: A Re-Evaluation of Diagnostic Tests for Scrub Typhus Using Bayesian LCMs.

The indirect immunofluorescence assay (IFA) is considered a reference test for scrub typhus. Recently, the Scrub Typhus Infection Criteria (STIC; a combination of culture, PCR assays and IFA IgM) were proposed as a reference standard for evaluating alternative diagnostic tests. Here, we use Bayesian...

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Bibliographic Details
Main Authors: Cherry Lim, Daniel H Paris, Stuart D Blacksell, Achara Laongnualpanich, Pacharee Kantipong, Wirongrong Chierakul, Vanaporn Wuthiekanun, Nicholas P J Day, Ben S Cooper, Direk Limmathurotsakul
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4449177?pdf=render