Cryo-EM structure of respiratory complex I at work

Cryo-EM structure of respiratory complex I at work

Mitochondrial complex I has a key role in cellular energy metabolism, generating a major portion of the proton motive force that drives aerobic ATP synthesis. The hydrophilic arm of the L-shaped ~1 MDa membrane protein complex transfers electrons from NADH to ubiquinone, providing the energy to driv...

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Bibliographic Details
Main Authors: Kristian Parey, Ulrich Brandt, Hao Xie, Deryck J Mills, Karin Siegmund, Janet Vonck, Werner Kühlbrandt, Volker Zickermann
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-10-01
Series:eLife
Subjects:
respiratory complex I
redox-linked proton translocation
active/deactive transition
Yarrowia lipolytica
Online Access:https://elifesciences.org/articles/39213

Internet

https://elifesciences.org/articles/39213

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