Constitutive Differential Features of Type 2 Transglutaminase in Cells Derived from Celiac Patients and from Healthy Subjects

Constitutive Differential Features of Type 2 Transglutaminase in Cells Derived from Celiac Patients and from Healthy Subjects

Type 2 transglutaminase (TG2) is a ubiquitous enzyme able to modify gliadin peptides introduced into the organism through the diet. By means of its catalytic activity, TG2 seems to have an important pathogenetic role in celiac disease (CD), an inflammatory intestinal disease caused by the ingestion...

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Bibliographic Details
Main Authors: Gaetana Paolella, Merlin Nanayakkara, Silvia Sposito, Marilena Lepretti, Salvatore Auricchio, Carla Esposito, Maria Vittoria Barone, Stefania Martucciello, Ivana Caputo
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
type 2 transglutaminase
celiac disease
gliadin peptide 31–43
celiac cellular phenotype
skin-derived fibroblasts
Online Access:https://www.mdpi.com/1422-0067/21/4/1231

Internet

https://www.mdpi.com/1422-0067/21/4/1231

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