Grape Seed Proanthocyanidins Induce Apoptosis through p53, Bax, and Caspase 3 Pathways

Grape seed proanthocyanidins (GSP) have been shown to inhibit skin chemical carcinogenesis and photocarcinogenesis in mice. The mechanisms responsible for the anticarcinogenic effects of GSP are not clearly understood. Here, we report that treatment of JB6 C141 cells (a well-developed cell culture...

Full description

Bibliographic Details
Main Authors: Anshu M. Roy, Manjeshwar S. Baliga, Craig A. Elmets, Santosh K. Katiyar
Format: Article
Language:English
Published: Elsevier 2005-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
p53
Bax
Online Access:http://www.sciencedirect.com/science/article/pii/S147655860580096X