CD4 T-cell expression of IFN-γ and IL-17 in pediatric malarial anemia.

In Plasmodium falciparum holoendemic transmission regions of western Kenya, life-threatening pediatric malaria manifests primarily as severe malarial anemia (SMA, Hb≤6.0 g/dL with any density parasitemia). To determine the role that CD4+ T-cell-driven inflammatory responses have in the pathogenesis...

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Bibliographic Details
Main Authors: Evans Raballah, Prakasha Kempaiah, Zachary Karim, George O Orinda, Michael F Otieno, Douglas J Perkins, John Michael Ong'echa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5398558?pdf=render