Upregulating MicroRNA-410 or Downregulating Wnt-11 Increases Osteoblasts and Reduces Osteoclasts to Alleviate Osteonecrosis of the Femoral Head

Upregulating MicroRNA-410 or Downregulating Wnt-11 Increases Osteoblasts and Reduces Osteoclasts to Alleviate Osteonecrosis of the Femoral Head

Abstract Background Little is known regarding the functional role of microRNA-410 (miR-410) in osteonecrosis of the femoral head (ONFH); hence, the aim of the present study was to investigate miR-410 targeting Wnt-11 to modulate the osteogenic and osteoclastic mechanism in the prevention of ONFH. Me...

Full description

Bibliographic Details
Main Authors: Yukun Yin, Lixiang Ding, Yu Hou, Haoran Jiang, Ji Zhang, Zhong Dai, Genai Zhang
Format: Article
Language:English
Published: SpringerOpen 2019-12-01
Series:Nanoscale Research Letters
Subjects:
MicroRNA-410
Wnt-11
Osteonecrosis of the femoral head
Osteoblasts
Osteoclasts
Online Access:https://doi.org/10.1186/s11671-019-3221-6

Internet

https://doi.org/10.1186/s11671-019-3221-6

Similar Items