Role of neuromedin B and its receptor in the innate immune responses against influenza A virus infection in vitro and in vivo

Abstract The peptide neuromedin B (NMB) and its receptor (NMBR) represent a system (NMB/NMBR) of neuromodulation. Here, it was demonstrated that the expression of NMBR in cells or murine lung tissues was clearly upregulated in response to H1N1/PR8 influenza A virus infection. Furthermore, the in vit...

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Bibliographic Details
Main Authors: Guihong Yang, Huipeng Huang, Mengyao Tang, Zifeng Cai, Cuiqin Huang, Baomin Qi, Ji-Long Chen
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Veterinary Research
Online Access:http://link.springer.com/article/10.1186/s13567-019-0695-2