Intermittent hypoxia inhibits mandibular cartilage growth with reduced TGF-β and SOX9 expressions in neonatal rats

Abstract Intermittent hypoxia (IH) has been associated with skeletal growth. However, the influence of IH on cartilage growth and metabolism is unknown. We compared the effects of IH on chondrocyte proliferation and maturation in the mandibular condyle fibrocartilage and tibial hyaline cartilage of...

Full description

Bibliographic Details
Main Authors: Kochakorn Lekvijittada, Jun Hosomichi, Hideyuki Maeda, Haixin Hong, Chidsanu Changsiripun, Yo-ichiro Kuma, Shuji Oishi, Jun-ichi Suzuki, Ken-ichi Yoshida, Takashi Ono
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80303-3