Wernicke’s encephalopathy — from basic science to clinical practice. Part 1: Understanding the role of thiamine

Wernicke’s encephalopathy (WE) is an acute neuropsychiatric state. Untreated, WE can lead to coma or death, or progress to Korsakoff syndrome (KS) – a dementia characterized by irreversible loss of anterograde memory. Thiamine (vitamin B1) deficiency lies at the heart of this condition. Yet, our und...

Full description

Bibliographic Details
Main Authors: Michael Ott, Ursula Werneke
Format: Article
Language:English
Published: SAGE Publishing 2020-12-01
Series:Therapeutic Advances in Psychopharmacology
Online Access:https://doi.org/10.1177/2045125320978106