Dysregulation of Lipid Metabolism in Mkp-1 Deficient Mice during Gram-Negative Sepsis

Dysregulation of Lipid Metabolism in Mkp-1 Deficient Mice during Gram-Negative Sepsis

Mitogen-activated protein kinase phosphatase (Mkp)-1 exerts its anti-inflammatory activities during Gram-negative sepsis by deactivating p38 and c-Jun N-terminal kinase (JNK). We have previously shown that <i>Mkp-1</i><sup>+/+</sup> mice, but not <i>Mkp-1</i><s...

Full description

Bibliographic Details
Main Authors: Jinhui Li, Xiantao Wang, William E. Ackerman, Abel J. Batty, Sean G. Kirk, William M. White, Xianxi Wang, Dimitrios Anastasakis, Lobelia Samavati, Irina Buhimschi, Leif D. Nelin, Markus Hafner, Yusen Liu
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:International Journal of Molecular Sciences
Subjects:
<i>E. coli</i> infection
sepsis
liver steatosis
hypertriglyceridemia
Mkp-1
Online Access:https://www.mdpi.com/1422-0067/19/12/3904

Internet

https://www.mdpi.com/1422-0067/19/12/3904

Similar Items