PRICKLE1 × FOCAD Interaction Revealed by Genome-Wide vQTL Analysis of Human Facial Traits

PRICKLE1 × FOCAD Interaction Revealed by Genome-Wide vQTL Analysis of Human Facial Traits

The human face is a highly complex and variable structure resulting from the intricate coordination of numerous genetic and non-genetic factors. Hundreds of genomic loci impacting quantitative facial features have been identified. While these associations have been shown to influence morphology by a...

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Bibliographic Details
Main Authors: Dongjing Liu, Hyo-Jeong Ban, Ahmed M. El Sergani, Myoung Keun Lee, Jacqueline T. Hecht, George L. Wehby, Lina M. Moreno, Eleanor Feingold, Mary L. Marazita, Seongwon Cha, Heather L. Szabo-Rogers, Seth M. Weinberg, John R. Shaffer
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Genetics
Subjects:
human facial traits
variance quantitative trait loci (vQTL)
gene-by-gene (G × G) interaction
Prickle1
Focadhesin
craniofacial
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.674642/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.674642/full

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