HIV Aspartic Peptidase Inhibitors Modulate Surface Molecules and Enzyme Activities Involved with Physiopathological Events in Fonsecaea pedrosoi

HIV Aspartic Peptidase Inhibitors Modulate Surface Molecules and Enzyme Activities Involved with Physiopathological Events in Fonsecaea pedrosoi

Fonsecaea pedrosoi is the main etiological agent of chromoblastomycosis, a recalcitrant disease that is extremely difficult to treat. Therefore, new chemotherapeutics to combat this fungal infection are urgently needed. Although aspartic peptidase inhibitors (PIs) currently used in the treatment of...

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Bibliographic Details
Main Authors: Vanila F. Palmeira, Daniela S. Alviano, Lys A. Braga-Silva, Fátima R. V. Goulart, Marcela Q. Granato, Sonia Rozental, Celuta S. Alviano, André L. S. Santos, Lucimar F. Kneipp
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Microbiology
Subjects:
chromoblastomycosis
Fonsecaea pedrosoi
peptidases
HIV aspartic peptidase inhibitors
antifungal action
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.00918/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.00918/full

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