In vivo analysis reveals that ATP-hydrolysis couples remodeling to SWI/SNF release from chromatin

ATP-dependent chromatin remodelers control the accessibility of genomic DNA through nucleosome mobilization. However, the dynamics of genome exploration by remodelers, and the role of ATP hydrolysis in this process remain unclear. We used live-cell imaging of Drosophila polytene nuclei to monitor Br...

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Bibliographic Details
Main Authors: Ben C Tilly, Gillian E Chalkley, Jan A van der Knaap, Yuri M Moshkin, Tsung Wai Kan, Dick HW Dekkers, Jeroen AA Demmers, C Peter Verrijzer
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/69424