Targeting Hypoxia-Driven Metabolic Reprogramming to Constrain Tumor Progression and Metastasis

Hypoxia in locally advanced solid tumors develops due to uncontrollable cell proliferation, altered metabolism, and the severe structural and functional abnormality of the tumor vasculature, leading to an imbalance between oxygen supply and consumption in the fast-growing tumors and negative impact...

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Bibliographic Details
Main Authors: Marisol Miranda-Galvis, Yong Teng
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/15/5487