Metabolomic Profiling of the Effects of Melittin on Cisplatin Resistant and Cisplatin Sensitive Ovarian Cancer Cells Using Mass Spectrometry and Biolog Microarray Technology
In the present study, liquid chromatography-mass spectrometry (LC-MS) was employed to characterise the metabolic profiles of two human ovarian cancer cell lines A2780 (cisplatin-sensitive) and A2780CR (cisplatin-resistant) in response to their exposure to melittin, a cytotoxic peptide from bee venom...
Main Authors: | Sanad Alonezi, Jonans Tusiimire, Jennifer Wallace, Mark J. Dufton, John A. Parkinson, Louise C. Young, Carol J. Clements, Jin Kyu Park, Jong Woon Jeon, Valerie A. Ferro, David G. Watson |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-10-01
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Series: | Metabolites |
Subjects: | |
Online Access: | http://www.mdpi.com/2218-1989/6/4/35 |
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