Deficiency of macrophage migration inhibitory factor (MIF) inhibits cytokine-induced IL-1β generation in murine pancreatic islet cells

In diabetes, pancreatic islets are subjected to high levels of inflammatory mediators that can lead to beta cell destruction. We recently showed that pancreatic islet cells derived from MIF-deficient (MIF-KO) mice are resistant to apoptosis induction by the cytotoxic stimuli of cytokines. Here we...

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Bibliographic Details
Main Authors: Stojanović Ivana, Saksida Tamara, Stošić-Grujičić Stanislava
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2013-01-01
Series:Archives of Biological Sciences
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2013/0354-46641301009S.pdf