Proteasome inhibitors: A rational for clinical use in the treatment of multiple myeloma
Proteasome inhibitors (PI) represent the class of medicaments which lead to inhibition of catalytic chymotrypsin-like proteolytic proteasome subunits. Blockade of this specific structure drives to complete ubiquitin-proteasome machinery withdrawal. Total intracellular protein flow is regulated by th...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Medicinsko društvo za racionalnu terapiju Republike Srbije
2016-01-01
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| Series: | Racionalna Terapija |
| Subjects: | |
| Online Access: | http://scindeks-clanci.ceon.rs/data/pdf/1821-0538/2016/1821-05381602025P.pdf |