The cis-Regulatory Element of SNCA Intron 4 Modulates Susceptibility to Parkinson’s Disease in Han Chinese

The cis-Regulatory Element of SNCA Intron 4 Modulates Susceptibility to Parkinson’s Disease in Han Chinese

Objective: A novel functional cis-regulatory element (CRE) located at SNCA intron 4 has recently been identified in association with Parkinson’s disease (PD) risk in European descendants. We aimed to investigate whether this CRE is associated with PD in Han Chinese ethnicity.Methods: A Chinese cohor...

Full description

Bibliographic Details
Main Authors: Shi-Guo Zhu, Hui Lu, Miao Mao, Zhao-Feng Li, Lei Cui, Begench Ovlyakulov, Xiong Zhang, Jian-Hong Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Genetics
Subjects:
Parkinson’s disease
SNCA
cis-regulatory element
association
variant
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.590365/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2020.590365/full

Similar Items