Sera from patients with sepsis induce nitric oxide production in vascular smooth muscle cells

Background: Nitric oxide (NO) is an important physiological mediator of vascular tone and is involved in pathophysiology of septic shock. Although plasma nitrite is a stable end product of NO oxidation derived from endogenous NO, the plasma nitrite level is also easily affected by the intake of vari...

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Bibliographic Details
Main Authors: Hiroshi Fujita, Junji Tomiyama, Hideki Kudo, Ikuo Morita, Sei-itsu Murota
Format: Article
Language:English
Published: Hindawi Limited 2000-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1080/09629350020027591