Spironolactone Reduces Aortic Stiffness in Patients With Resistant Hypertension Independent of Blood Pressure Change

Spironolactone Reduces Aortic Stiffness in Patients With Resistant Hypertension Independent of Blood Pressure Change

Background Aortic stiffness is an independent predictor of cardiovascular events in patients with arterial hypertension. Resistant hypertension is often linked to hyperaldosteronism and associated with adverse outcomes. Spironolactone, a mineralocorticoid receptor antagonist, has been shown to reduc...

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Bibliographic Details
Main Authors: Sudeep R. Aryal, Mohammed Siddiqui, Oleg F. Sharifov, Megan D. Coffin, Bin Zhang, Krishna K. Gaddam, Himanshu Gupta, Thomas S. Denney, Louis J. Dell'Italia, Suzanne Oparil, David A. Calhoun, Steven G. Lloyd
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
aorta
hyperaldosteronism
resistant hypertension
spironolactone
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.120.019434

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.120.019434

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