Association between polymorphisms in the TSHR gene and Graves' orbitopathy.

Association between polymorphisms in the TSHR gene and Graves' orbitopathy.

BACKGROUND:Graves' orbitopathy (GO) as well as Graves' disease (GD) hyperthyroidism originate from an autoimmune reaction against the common auto-antigen, thyroid-stimulating hormone receptor (TSHR). GO phenotype is associated with environmental risk factors, mainly nicotinism, as well as...

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Main Authors: Beata Jurecka-Lubieniecka, Rafal Ploski, Dorota Kula, Konrad Szymanski, Tomasz Bednarczuk, Urszula Ambroziak, Kornelia Hasse-Lazar, Lidia Hyla-Klekot, Andrzej Tukiendorf, Zofia Kolosza, Barbara Jarzab
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4111286?pdf=render

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http://europepmc.org/articles/PMC4111286?pdf=render

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