Pharmacological inhibition of EZH2 disrupts the female germline epigenome

Abstract Background Recently discovered drugs that target epigenetic modifying complexes are providing new treatment options for a range of cancers that affect patients of reproductive age. Although these drugs provide new therapies, it is likely that they will also affect epigenetic programming in...

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Bibliographic Details
Main Authors: Lexie Prokopuk, Kirsten Hogg, Patrick S. Western
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Clinical Epigenetics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13148-018-0465-4