Sorting Nexin 10 as a Key Regulator of Membrane Trafficking in Bone-Resorbing Osteoclasts: Lessons Learned From Osteopetrosis

Sorting Nexin 10 as a Key Regulator of Membrane Trafficking in Bone-Resorbing Osteoclasts: Lessons Learned From Osteopetrosis

Bone homeostasis is a complex, multi-step process, which is based primarily on a tightly orchestrated interplay between bone formation and bone resorption that is executed by osteoblasts and osteoclasts (OCLs), respectively. The essential physiological balance between these cells is maintained and c...

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Bibliographic Details
Main Authors: Ari Elson, Merle Stein, Grace Rabie, Maayan Barnea-Zohar, Sabina Winograd-Katz, Nina Reuven, Moran Shalev, Juraj Sekeres, Moien Kanaan, Jan Tuckermann, Benjamin Geiger
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
osteoclast
osteopetrosis
ARO
sorting nexin
SNX10
bone resorption
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.671210/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.671210/full

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