C6/36 Aedes albopictus cells have a dysfunctional antiviral RNA interference response.

Mosquitoes rely on RNA interference (RNAi) as their primary defense against viral infections. To this end, the combination of RNAi and invertebrate cell culture systems has become an invaluable tool in studying virus-vector interactions. Nevertheless, a recent study failed to detect an active RNAi r...

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Bibliographic Details
Main Authors: Doug E Brackney, Jaclyn C Scott, Fumihiko Sagawa, Jimmy E Woodward, Neil A Miller, Faye D Schilkey, Joann Mudge, Jeffrey Wilusz, Ken E Olson, Carol D Blair, Gregory D Ebel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21049065/pdf/?tool=EBI