Vaccination with a plasmid DNA encoding HER-2/neu together with low doses of GM-CSF and IL-2 in patients with metastatic breast carcinoma: a pilot clinical trial

<p>Abstract</p> <p>Background</p> <p>Adjuvant trastuzumab (Herceptin) treatment of breast cancer patients significantly improves their clinical outcome. Vaccination is an attractive alternative approach to provide HER-2/neu (Her2)-specific antibodies and may in addition...

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Bibliographic Details
Main Authors: Knutson Keith L, Piechocki Marie P, Erskine Courtney, Wei Wei Z, Charo Jehad, Poschke Isabel, Norell Håkan, Bergh Jonas, Lidbrink Elisabet, Kiessling Rolf
Format: Article
Language:English
Published: BMC 2010-06-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/8/1/53