Mitochondrial protein IF1 is a potential regulator of glucagon-like peptide (GLP-1) secretion function of the mouse intestine

Mitochondrial protein IF1 is a potential regulator of glucagon-like peptide (GLP-1) secretion function of the mouse intestine

IF1 (ATPIF1) is a nuclear DNA-encoded mitochondrial protein whose activity is inhibition of the F1Fo-ATP synthase to control ATP production. IF1 activity remains unknown in the regulation of GLP-1 activity. In this study, IF1 was examined in the diet-induced obese mice using the gene knockout (If1-K...

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Bibliographic Details
Main Authors: Ying Wang, Jiaojiao Zhang, Xinyu Cao, Yaya Guan, Shuang Shen, Genshen Zhong, Xiwen Xiong, Yanhong Xu, Xiaoying Zhang, Hui Wang, Jianping Ye
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Acta Pharmaceutica Sinica B
Subjects:
GLP-1
ATPIF1
ANT2
L-cells
Mitophagy
Microbiota
Online Access:http://www.sciencedirect.com/science/article/pii/S221138352100040X

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http://www.sciencedirect.com/science/article/pii/S221138352100040X

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