Hypertension Accelerates Alzheimer’s Disease-Related Pathologies in Pigs and 3xTg Mice

Hypertension Accelerates Alzheimer’s Disease-Related Pathologies in Pigs and 3xTg Mice

Epidemiological studies suggest there is an association between midlife hypertension and increased risk of late-life Alzheimer’s disease (AD). However, whether hypertension accelerates the onset of AD or is a distinct disease that becomes more prevalent with age (comorbidity) remains unclear. This s...

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Bibliographic Details
Main Authors: Yao-Hsiang Shih, Shih-Ying Wu, Megan Yu, Sheng-Huai Huang, Chu-Wan Lee, Meei-Jyh Jiang, Pao-Yen Lin, Ting-Ting Yang, Yu-Min Kuo
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Aging Neuroscience
Subjects:
hypertension
Alzheimer’s disease
hippocampus
learning and memory
Aβ
tau
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2018.00073/full

Internet

http://journal.frontiersin.org/article/10.3389/fnagi.2018.00073/full

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