Mechanisms of iron metabolism in Caenorhabditis elegans

Iron is involved in many biological processes essential for sustaining life. In excess, iron is toxic due to its ability to catalyze the formation of free radicals that damage macromolecules. Organisms have developed specialized mechanisms to tightly regulate iron uptake, storage and efflux. Ove...

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Bibliographic Details
Main Authors: Elizabeth A Leibold, Cole P Anderson
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00113/full