Peripheral blood monocyte Sirt1 expression is reduced in patients with coronary artery disease.

Peripheral blood monocyte Sirt1 expression is reduced in patients with coronary artery disease.

BACKGROUND: Inflammation plays a key role in atherosclerosis. Sirt1 regulates transcription factors involved in inflammatory processes and blunts atherosclerosis in mice. However, its role in humans remains to be defined. This study was therefore designed to investigate the role of Sirt1 in the deve...

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Bibliographic Details
Main Authors: Alexander Breitenstein, Christophe A Wyss, Remo D Spescha, Fabian C Franzeck, Danielle Hof, Meliana Riwanto, Matthias Hasun, Alexander Akhmedov, Arnold von Eckardstein, Willibald Maier, Ulf Landmesser, Thomas F Lüscher, Giovanni G Camici
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3558418?pdf=render

Internet

http://europepmc.org/articles/PMC3558418?pdf=render

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