Study designs to investigate Nox1 acceleration of neoplastic progression in immortalized human epithelial cells by selection of differentiation resistant cells

Study designs to investigate Nox1 acceleration of neoplastic progression in immortalized human epithelial cells by selection of differentiation resistant cells

To investigate the role of NADPH oxidase homolog Nox1 at an early step of cell transformation, we utilized human gingival mucosal keratinocytes immortalized by E6/E7 of human papillomavirus (HPV) type 16 (GM16) to generate progenitor cell lines either by chronic ethanol exposure or overexpression w...

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Bibliographic Details
Main Authors: Apsorn Sattayakhom, Warangkana Chunglok, Wanida Ittarat, Walee Chamulitrat
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Redox Biology
Subjects:
Immortalized gingival keratinocytes
Spindle cells
Cobblestone cells
Intermediate filaments
Cytokeratins
EMT
Invasion
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231713000980

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http://www.sciencedirect.com/science/article/pii/S2213231713000980

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