Protein-DNA interactions define the mechanistic aspects of circle formation and insertion reactions in IS<it>2 </it>transposition

Protein-DNA interactions define the mechanistic aspects of circle formation and insertion reactions in IS<it>2 </it>transposition

<p>Abstract</p> <p>Background</p> <p>Transposition in IS<it>3</it>, IS<it>30</it>, IS<it>21 </it>and IS<it>256 </it>insertion sequence (IS) families utilizes an unconventional two-step pathway. A figure-of-eight intermedia...

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Bibliographic Details
Main Authors: Lewis Leslie A, Astatke Mekbib, Umekubo Peter T, Alvi Shaheen, Saby Robert, Afrose Jehan, Oliveira Pedro H, Monteiro Gabriel A, Prazeres Duarte MF
Format: Article
Language:English
Published: BMC 2012-01-01
Series:Mobile DNA
Subjects:
Curvature propensity plot data
extensive sequence-specific binding
figure-of-eight transposition intermediate
hydroxyl radical footprinting
minicircle junction
selective binding
synaptic complex
transpososome
Online Access:http://www.mobilednajournal.com/content/3/1/1

Internet

http://www.mobilednajournal.com/content/3/1/1

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