PDGFRB Promotes Liver Metastasis Formation of Mesenchymal-Like Colorectal Tumor Cells

PDGFRB Promotes Liver Metastasis Formation of Mesenchymal-Like Colorectal Tumor Cells

In epithelial tumors, the platelet-derived growth factor receptor B (PDGFRB) is mainly expressed by stromal cells of mesenchymal origin. Tumor cells may also acquire PDGFRB expression following epithelial-to-mesenchymal transition (EMT), which occurs during metastasis formation. Little is known abo...

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Bibliographic Details
Main Authors: Ernst J.A. Steller, Danielle A. Raats, Jan Koster, Bert Rutten, Klaas M. Govaert, Benjamin L. Emmink, Nikol Snoeren, Sander R. van Hooff, Frank C.P. Holstege, Coen Maas, Rinkes Inne H.M. Borel, Onno Kranenburg
Format: Article
Language:English
Published: Elsevier 2013-02-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558613800309

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http://www.sciencedirect.com/science/article/pii/S1476558613800309

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