A combination of curcumin, vorinostat and silibinin reverses Aβ-induced nerve cell toxicity via activation of AKT-MDM2-p53 pathway

Alzheimer’s disease (AD) is a significant health issue for the elderly and becoming increasingly common as the global population ages. Although many efforts have been made to elucidate its pathology, there is still a lack of effective clinical anti-AD agents. Previous research has shown the neuropro...

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Bibliographic Details
Main Authors: Jia Meng, Yan Li, Mingming Zhang, Wenjing Li, Lin Zhou, Qiujun Wang, Lin Lin, Lihong Jiang, Wenliang Zhu
Format: Article
Language:English
Published: PeerJ Inc. 2019-04-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/6716.pdf